Description
Ceritinib 150 mg – Targeted Therapy for ALK-Positive Non-Small Cell Lung Cancer
Ceritinib 150 mg is an oral anti-cancer medication used in the treatment of ALK-positive metastatic non-small cell lung cancer (NSCLC). It works by inhibiting the activity of an abnormal anaplastic lymphoma kinase (ALK) protein, which helps stop the growth and spread of cancer cells.
Key Features:
- Used to treat ALK-positive NSCLC in adults
- Belongs to the class of tyrosine kinase inhibitors (TKIs)
- May be used in patients resistant to or intolerant of crizotinib
- Oral capsule – convenient once-daily dosing
- Available under brand names like Zykadia or in generic form
How to Use:
Take Ceritinib exactly as prescribed by your oncologist. It is usually taken once daily on an empty stomach, at least 2 hours before or after food. Swallow capsules whole with water. Do not crush or chew.
Precautions:
- Regular liver function tests, blood sugar, and ECG monitoring may be required
- Not recommended during pregnancy or breastfeeding
- May interact with other medications – inform your doctor of all drugs you’re taking
- Watch for signs of liver problems, lung inflammation, or severe gastrointestinal issues
Storage Instructions:
Store at room temperature (15–30°C) in a dry place, away from light and moisture. Keep out of reach of children and pets.
Frequently Asked Questions (FAQs)
1. What is Ceritinib 150 mg used for?
Ceritinib 150 mg is used to treat patients with ALK-positive metastatic non-small cell lung cancer (NSCLC), particularly those who have progressed on or are intolerant to crizotinib.
2. How does Ceritinib work?
It works by blocking abnormal ALK proteins that drive the growth of cancer cells in certain lung cancers.
3. What are the common side effects of Ceritinib?
Common side effects include nausea, vomiting, diarrhea, liver enzyme elevations, abdominal pain, fatigue, and loss of appetite. Serious side effects may include interstitial lung disease, QT prolongation, or hyperglycemia.
4. How should I take Ceritinib?
Take it once daily on an empty stomach, at least 2 hours before or after food. Always follow your doctor’s instructions exactly.
5. Can Ceritinib 150 mg cure lung cancer?
Ceritinib is not a cure, but it can significantly slow disease progression and improve quality of life in patients with ALK-positive NSCLC.
6. Is Ceritinib safe during pregnancy?
No. Ceritinib may harm an unborn baby. Effective contraception should be used during treatment and for at least several weeks after the last dose.
7. Does Ceritinib interact with other medications?
Yes. Ceritinib can interact with several drugs, including certain antifungals, antibiotics, antiepileptics, and heart medications. Inform your doctor about all medicines you are taking.
