Description
Leuprolide Acetate 1 mg Injection – GnRH Agonist for Hormone-Related Conditions
Leuprolide Acetate 1 mg injection is a gonadotropin-releasing hormone (GnRH) agonist used to treat hormone-sensitive conditions such as prostate cancer, endometriosis, uterine fibroids, and precocious puberty. It works by reducing the production of certain hormones like estrogen and testosterone, helping control the growth of hormone-dependent tumors or tissue.
Key Benefits:
- Reduces testosterone in men (prostate cancer)
- Controls estrogen production in women (endometriosis, fibroids)
- Used in fertility treatments to suppress natural ovulation
- Helps manage central precocious puberty in children
- Once-daily subcutaneous injection for precise hormone regulation
How to Use:
This injection is typically administered subcutaneously (under the skin) once daily, or as directed by a physician. Always follow proper administration technique and medical instructions.
Precautions:
- For use under strict medical supervision only
- Do not use if pregnant or breastfeeding
- May initially cause a temporary hormone surge (flare effect)
- Inform your doctor if you have diabetes, heart issues, or depression
- Bone density may decrease with long-term use – monitor regularly
Storage Instructions:
Store in a refrigerator at 2–8°C. Do not freeze. Protect from light. Keep out of reach of children.
Frequently Asked Questions (FAQs)
1. What is Leuprolide Acetate 1 mg used for?
It is used to treat prostate cancer in men, endometriosis and fibroids in women, central precocious puberty in children, and also in fertility treatments.
2. How does Leuprolide work?
Leuprolide suppresses the production of sex hormones (testosterone and estrogen) by overstimulating the pituitary gland, leading to hormonal downregulation.
3. How is Leuprolide administered?
It is given as a subcutaneous injection, usually once a day or as scheduled by your doctor. Long-acting formulations may be available for monthly use.
4. Can Leuprolide be used in fertility treatments?
Yes, it is often used to suppress natural ovulation during in-vitro fertilization (IVF) protocols, allowing controlled ovarian stimulation.
5. What are the side effects of Leuprolide Acetate 1 mg injection?
Common side effects include hot flashes, headache, decreased libido, injection site reactions, mood changes, and bone thinning with long-term use.
6. Is Leuprolide Acetate 1 mg injection safe during pregnancy?
No. Leuprolide should not be used during pregnancy or while breastfeeding. Use effective contraception during treatment.
7. What is the “flare effect” of Leuprolide?
The flare effect is a temporary increase in hormone levels at the start of treatment before suppression occurs. This can temporarily worsen symptoms in some patients.
